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Lincomycin (hydrochloride)

Lincomycin (hydrochloride)

Item no.	HY-B0417A-10mg
Manufacturer	MedChem Express
CASRN	859-18-7
Amount	10 mg
Quantity options	100 mg 10 mg 1 ea 1 g 500 mg 5 g 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.29
Citations	[1]Griaznova, N.S., et al., [Effect of lincomycin and other protein synthesis inhibitors on the metabolism of Actinomyces roseolus, a producer of lincomycin]. Antibiotiki, 1980. 25(4): p. 250-6.\|[2]Hummel, H., W. Piepersberg, and A. Bock, Analysis of lincomycin resistance mutations in Escherichia coli. Mol Gen Genet, 1979. 169(3): p. 345-7.\|[3]Champney, W.S. and C.L. Tober, Specific inhibition of 50S ribosomal subunit formation in Staphylococcus aureus cells by 16-membered macrolide, lincosamide, and streptogramin B antibiotics. Curr Microbiol, 2000. 41(2): p. 126-35.
Smiles	C[C@@H](O)[C@@]([C@@]([C@@H]([C@H](O)[C@H]1O)O)([H])O[C@@H]1SC)([H])NC([C@@H]2C[C@@H](CCC)CN2C)=O.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	U10149A
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Antibiotic; Bacterial; DNA/RNA Synthesis
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	443.00
Product Description	Lincomycin hydrochloride is the salt form of the antibiotic lincomycin. Lincomycin can affect the synthesis of protein, RNA and DNA in the mycelium of the lincomycin-producing organism Act. Roseolus. Lincomycin inhibits protein synthesis in gram-positive and - to a lower degree - also in gram-negative bacteria. Lincomycin binds to the 50S subunits of bacterial ribosomes and act on aminoacyl-tRNA binding and the transpeptidation reaction[1][2][3].
Manufacturer - Research Area	Infection
Solubility	H2O: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection; Cell Cycle/DNA Damage
Clinical information	Launched

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Amount: 10 mg

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