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Nabumetone-d3

Nabumetone-d3

Item no.	HY-B0559S-1mg
Manufacturer	MedChem Express
CASRN	1216770-08-9
Amount	1 mg
Quantity options	10 mg 1 mg 2.5 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Citations	[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. \|[2]Vural F, et al. Cyclo-oxygenase 2 inhibitor, nabumetone, inhibits proliferation in chronic myeloid leukemia cell lines. Leuk Lymphoma. 2005 May;46(5):753-6.\|[3]Melarange R, et al. Anti-inflammatory and gastrointestinal effects of nabumetone or its active metabolite, 6MNA (6-methoxy-2-naphthylacetic acid): comparison with indomethacin. Agents Actions. 1992;Spec No:C82-3.
Smiles	CC(CCC1=CC2=C(C=C1)C=C(C=C2)OC([2H])([2H])[2H])=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	BRL14777-d3
Shipping Condition	Room temperature
Available
Manufacturer - Type	Isotope-Labeled Compounds
Manufacturer - Targets	COX; Isotope-Labeled Compounds
Shipping Temperature	Room temperature
Molecular Weight	231.30
Product Description	Nabumetone-d3 is the deuterium labeled Nabumetone. Nabumetone is an orally active non-acidic anti-inflammatory agent, acts as a potent and selective COX-2 inhibitor, and is the proagent of the active metabolite 6MNA.
Manufacturer - Research Area	Inflammation/Immunology; Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	Immunology/Inflammation; Others
Clinical information	No Development Reported

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