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Deupirfenidone

Deupirfenidone

Item no.	HY-B0673S1-5mg
Manufacturer	MedChem Express
CASRN	1093951-85-9
Amount	5 mg
Quantity options	10 mg 1 ea 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.60
Citations	[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-243.
Smiles	O=C1N(C2=CC=CC=C2)C=C(C=C1)C([2H])([2H])[2H]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	LYT-100,AMR69-d3
Shipping Condition	Room temperature
Available
Manufacturer - Type	Isotope-Labeled Compounds
Manufacturer - Targets	Isotope-Labeled Compounds
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	188.24
Product Description	Deupirfenidone-d3 is the deuterium labeled Pirfenidone (HY-B0673). Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities[1][2][3].
Manufacturer - Research Area	Others
Solubility	DMSO: ≥ 100mg/mL\|H2O: 12.5mg/mL (ultrasonic)
Manufacturer - Pathway	Others
Clinical information	Phase 2

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HY-B0673S1-5mg-safety-datasheet.pdf