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Limaprost-d3

Limaprost-d3

Item no.	HY-B0683S-5mg
Manufacturer	MedChem Express
CASRN	1263190-37-9
Amount	5 mg
Quantity options	500 ug 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Citations	[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.\|[2]Tsuboi T, et al. Pharmacological evaluation of OP 1206, a prostaglandin E1 derivative, as an antianginal agent. Arch Int Pharmacodyn Ther. 1980 Sep;247(1):89-102.\|[3]Swainston Harrison T, et al. Limaprost. Drugs. 2007;67(1):109-18; discussion 119-20.\|[4]Murata K, et al. PGE1 Attenuates IL-1β-induced NGF Expression in Human Intervertebral Disc Cells. Spine (Phila Pa 1976). 2016 Jun;41(12):E710-6.
Smiles	C(CCCC=CC(O)=O)[C@@H]1[C@@H](C=C[C@H](C[C@H](CCCC)[C@]([2H])([2H])[2H])O)[C@H](O)CC1=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Isotope-Labeled Compounds
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Isotope-Labeled Compounds; PGE synthase
Shipping Temperature	Room temperature
Molecular Weight	383.54
Product Description	Limaprost-d3 (17α, 20-dimethyl-δ2-PGE1-d3) is the deuterium labeled Limaprost. Limaprost (OP1206) is a PGE1 analogue and a potent and orally active vasodilator. Limaprost increases blood flow and inhibits platelet aggregation. Limaprost pain relief, has antianginal effects, and can be used for ischaemic symptoms research[1][2].
Manufacturer - Research Area	Inflammation/Immunology; Cardiovascular Disease
Solubility	10 mM in DMSO
Manufacturer - Pathway	Immunology/Inflammation; Others
Clinical information	No Development Reported

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