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Phenylephrine

Phenylephrine

Item no.	HY-B0769-500mg
Manufacturer	MedChem Express
CASRN	59-42-7
Amount	500 mg
Quantity options	10 mM/1 mL 200 mg 500 mg
Category	Cardiovascular Research Hypertension Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.98
Citations	[1]Ford AP, et al. Pharmacological pleiotropism of the human recombinant alpha1A-adrenoceptor: implications foralpha1-adrenoceptor classification. Br J Pharmacol. 1997 Jul;121(6):1127-35.\|[2]Minneman KP, et al. Selectivity of agonists for cloned alpha 1-adrenergic receptor subtypes. Mol Pharmacol. 1994 Nov;46(5):929-36.\|[3]Wang J, et al. Phenylephrine promotes cardiac fibroblast proliferation through calcineurin-NFAT pathway. Front Biosci (Landmark Ed). 2016 Jan 1;21:502-13.\|[4]Lazou A, et al. Activation of mitogen-activated protein kinases (p38-MAPKs, SAPKs/JNKs and ERKs) by the G-protein-coupled receptor agonist phenylephrine in the perfused rat heart. Biochem J. 1998 Jun 1;332 ( Pt 2):459-65.\|[5]Li NJ, et al. Effect of phenylephrine on alveolar fluid clearance in ventilator-induced lung injury. Chin Med Sci J. 2013 Mar;28(1):1-6. Biochem Biophys Res Commun. 2024 Oct 17:735:150844.\|Biochim Biophys Acta Mol Basis Dis. 2023 Aug 27;166859.\|Biochim Biophys Acta Mol Basis Dis. 2024 Aug 30:167488.\|BMC Cardiovasc Disord. 2025 Jan 6;25(1):7.\|BMC Pulm Med. 2021 Jun 5;21(1):189.\|Eur J Pharmacol. 2025 Feb 1:177346.\|Front Med. 2024 May 14.\|J Cardiovasc Pharmacol. 2022 Sep 1;80(3):430-441.\|J Endod. 2023 Sep 26:S0099-2399(23)00608-8.\|J Ethnopharmacol. 2024 Aug 22:118707.\|Mol Med Rep. July 6, 2021.\|Nat Commun. 2024 Jul 16;15(1):5985.\|Sci Rep. 2023 Oct 2;13(1):16550.\|Trends Biotechnol. 2025 Jan 7:S0167-7799(24)00355-X.\|Elife. 2024 May 29.\|Free Radic Biol Med. 2024 Jan 6:S0891-5849(24)00007-8.\|Front Cardiovasc Med. 2021 Jun 16;8:679240.\|J Cell Mol Med. 2025 Mar;29(5):e70488.\|J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Aug 15;1092:220-227.
Smiles	O[C@H](C1=CC(O)=CC=C1)CNC
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	(R)-(-)-Phenylephrine,L-Phenylephrine
Similar products	59-42-7
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	Adrenergic Receptor
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	167.208
Product Description	(R)-(-)-Phenylephrine is a selective α1-adrenoceptor agonist primarily used as a decongestant.
Manufacturer - Research Area	Cardiovascular Disease; Endocrinology; Cancer
Solubility	DMSO: 50 mg/mL (ultrasonic)\|H2O: 5 mg/mL (ultrasonic)
Manufacturer - Pathway	GPCR/G Protein; Neuronal Signaling
Isoform	α adrenergic receptor
Clinical information	Launched

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HY-B0769-500mg-safety-datasheet.pdf