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Theophylline-d6

Theophylline-d6

Item no.	HY-B0809S-500ug
Manufacturer	MedChem Express
CASRN	117490-39-8
Amount	500 ug
Quantity options	1 ea 1 mg 500 ug 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.90
Citations	[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. \|[2]Deree J, et al. Insights into the regulation of TNF-alpha production in human mononuclear cells: the effects of non-specific phosphodiesterase inhibition. Clinics (Sao Paulo). 2008 Jun;63(3):321-8.\|[3]Marques LJ, et al. Pentoxifylline inhibits TNF-alpha production from human alveolar macrophages. Am J Respir Crit Care Med. 1999 Feb;159(2):508-11.\|[4]Daly JW, et al. Adenosine receptors: development of selective agonists and antagonists. Prog Clin Biol Res. 1987;230:41-63.
Smiles	O=C(N1C([2H])([2H])[2H])N(C([2H])([2H])[2H])C2=C(N=CN2)C1=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1,3-Dimethylxanthine-d6,Theo-24-d6
Shipping Condition	Room temperature
Available
Manufacturer - Type	Isotope-Labeled Compounds
Manufacturer - Targets	Adenosine Receptor; Autophagy; Endogenous Metabolite; Phosphodiesterase (PDE)
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	186.20
Product Description	Theophylline-d6 is the deuterium labeled Theophylline. Theophylline is a nonselective phosphodiesterase (PDE) inhibitor, adenosine receptor blocker, and histone deacetylase (HDAC) activator.
Manufacturer - Research Area	Cancer
Solubility	10 mM in DMSO\|DMF: ≥ 10mg/mL\|DMSO: ≥ 10mg/mL\|Ethanol: ≥ 1mg/mL
Manufacturer - Pathway	Autophagy; GPCR/G Protein; Metabolic Enzyme/Protease
Clinical information	No Development Reported

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HY-B0809S-500ug-safety-datasheet.pdf