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Pindolol-d7

Pindolol-d7

Item no.	HY-B0982S-10mg
Manufacturer	MedChem Express
CASRN	1185031-19-9
Amount	10 mg
Quantity options	10 mg 1 mg 2.5 mg 25 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Citations	[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.\|[2]Patkar OL, et al., Pindolol Rescues Anxiety-Like Behavior and Neurogenic Maladaptations of Long-Term Binge Alcohol Intake in Mice. Front Behav Neurosci. 2019 Nov 29;13:264.\|[3]Fernandes E, et al., Pindolol is a potent scavenger of reactive nitrogen species. Life Sci. 2005 Sep 2;77(16):1983-92.
Smiles	O(CC(CNC(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])O)C1=C2C(NC=C2)=CC=C1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Isotope-Labeled Compounds
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	5-HT Receptor; Adrenergic Receptor; Isotope-Labeled Compounds
Shipping Temperature	Room temperature
Molecular Weight	255.36
Product Description	Pindolol-d7 (LB-46-d7) is the deuterium labeled Pindolol. Pindolol (LB-46) is the antagonist for 5-HT 1A (Ki=33 nM) and 5-HT 1B. Pindolol is the antagonist for β1/β2-adrenergic receptor. Pindolol exhibits anti-anxiety and antidepressant effects[1][2].
Manufacturer - Research Area	Neurological Disease
Solubility	10 mM in DMSO
Manufacturer - Pathway	GPCR/G Protein; Neuronal Signaling; Others
Isoform	5-HT1 Receptor
Clinical information	No Development Reported

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Amount: 10 mg

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