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Nitroxoline-d4

Nitroxoline-d4

Item no.	HY-B1159S-1mg
Manufacturer	MedChem Express
Amount	1 mg
Quantity options	10 mg 1 ea 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	0.999
Citations	[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. \|[2]Abouelhassan Y, et al. Nitroxoline: a broad-spectrum biofilm-eradicating agent against pathogenic bacteria. Int J Antimicrob Agents. 2017 Feb;49(2):247-251.
Smiles	OC1=C2N=C([2H])C([2H])=C([2H])C2=C([N+]([O-])=O)C=C1[2H]
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	8-Hydroxy-5-nitroquinoline-D4,5-Nitro-8-quinolinol-D4
Shipping Condition	Room temperature
Available
Manufacturer - Type	Isotope-Labeled Compounds
Manufacturer - Targets	Antibiotic; Autophagy; Bacterial
Shipping Temperature	Room temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	194.18
Product Description	Nitroxoline-d4 is the deuterium labeled Nitroxoline. Nitroxoline is an antibiotic that has proven to be very effective at combating biofilm infections. Nitroxoline functions by chelating Fe2+ and Zn2+ ions from the biofilm matrix[1][2].
Manufacturer - Research Area	Infection; Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	Anti-infection; Autophagy
Clinical information	No Development Reported

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