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Cyromazine

Cyromazine

Item no.	HY-B1331-5g
Manufacturer	MedChem Express
CASRN	66215-27-8
Amount	5 g
Quantity options	100 mg 10 mM/1 mL 5 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.79
Formula	C6H10N6
Citations	[1]Levot GW, et al. Survival advantage of cyromazine-resistant sheep blowfly larvae on dicyclanil- and cyromazine-treated Merinos. Aust Vet J. 2014 Nov;92(11):421-6. [2]Khalid MZ, et al. Cyromazine Effects the Reproduction of Drosophila by Decreasing the Number of Germ Cells in the Female Adult Ovary[J]. Insects. 2022 Apr 27;13(5):414. [3]T. Heikal, A. Mossa, et al. Cyromazine and Chlorpyrifos Induced Renal Toxicity in Rats: The Ameliorated Effects of Green Tea Extract[J]. Journal of Environmental and Analytical Toxicology. 2012 June 9; 2(5): 1000146. [4]Khalid MZ, et al. Cyromazine affects the ovarian germ cells of Drosophila via the ecdysone signaling pathway[J]. Front Physiol. 2022 Sep 29;13:992306. [5]TAREK M.HEIKAL, et al. The ameliorating effects of green tea extract against cyromazine and chlorpyrifos induced liver toxicity in male rats[J]. Asian Journal of Pharmaceutical and Clinical Research. 2013 January; 6(1):47-55.
Smiles	NC1=NC(N)=NC(NC2CC2)=N1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Cyromazin, CGA-72662
Shipping condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Endogenous Metabolite; Parasite
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	166.18
Product Description	Cyromazine (CGA-72662) is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects. Cyromazine reduced the number of germ cells by interfering with the Ecdysone (HY-N0179) signaling pathway. Cyromazine induces renal toxicity attenuated and restored by green tea extract in rats[1][2][3][4][5].
Manufacturer - Research Area	Metabolic Disease; Neurological Disease
Solubility	DMSO : 200 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection; Metabolic Enzyme/Protease
Isoform	Human Endogenous Metabolite
Clinical information	No Development Reported

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HY-B1331-5g-safety-datasheet.pdf