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Furazolidone

Furazolidone

Item no.	HY-B1336-100mg
Manufacturer	MedChem Express
CASRN	67-45-8
Amount	100 mg
Quantity options	100 mg 10 mM/1 mL 1 g 500 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.87
Citations	[1]Jiang X, et al. A novel application of furazolidone: anti-leukemic activity in acute myeloid leukemia. PLoS One. 2013 Aug 9;8 (8) :e72335.\|[2]Ma S, et al. Furazolidone Increases Survival of Mice Exposed to Lethal Total Body Irradiation through the Antiapoptosis and Antiautophagy Mechanism. Oxid Med Cell Longev. 2021 Feb 4;2021:6610726.
Smiles	O=C1OCCN1/N=C/C2=CC=C([N+]([O-])=O)O2
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	67-45-8
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Antibiotic; Apoptosis; Bacterial; Parasite
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	225.16
Product Description	Furazolidone is a monoamine oxidase (MAO) inhibitor with antiproliferative, apoptosis-inducing and differentiation-promoting activities. Furazolidone may inhibit leukemia fusion protein-mediated bone marrow transformation by upregulating the stability of the tumor suppressor protein p53. Furazolidone exhibits anti-leukemic activity in acute myeloid leukemia (AML) cell lines and can be used for anti-AML research[1][2].
Manufacturer - Research Area	Infection; Cancer
Solubility	DMSO: 5.56 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Anti-infection; Apoptosis
Clinical information	Launched

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HY-B1336-100mg-safety-datasheet.pdf