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Frovatriptan succinate hydrate

Frovatriptan succinate hydrate

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	5mg
Item no.	HY-B1658A-5mg
CASRN	158930-17-7
Available
Product Description	Frovatriptan succinate hydrate ((R)-Frovatriptan succinate hydrate) is a potent, high affinity, selective and orally active 5-HT1B (pK50 of 8.2) and 5-HT1D receptor agonist. Frovatriptan succinate hydrate exhibits >10-fold selectivity for 5-HT1B and 5-HT1D over 5-HT1A, 5-HT1F, and 5-HT7 and >1000-fold selectivity over other 5-HT, dopamine, histamine H1, and α1-adrenoceptor. Frovatriptan succinate hydrate has the potential for migraine research.
StorageTemperature	-20°C, sealed storage, away from moisture; In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Applications	Neuroscience-Neuromodulation
Formula	C18H25N3O6
References	[1].Kelman L. Review of frovatriptan in the treatment of migraine. Neuropsychiatr Dis Treat. 2008 Feb; 4(1):49-54. \| [2].Comer MB. Et al. Pharmacology of the selective 5-HT(1B/1D) agonist frovatriptan. Headache. 2002 Apr; 42 Suppl 2:S47-53.
MolecularWeight	379.41
Research Area	Neurological Disease
Solubility	DMSO : 100 mg/mL (263.57 mM; Need ultrasonic)
Target	5-HT Receptor
Isoform	5-HT1B Receptor; 5-HT1D Receptor
Pathway	GPCR/G Protein; Neuronal Signaling

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Amount: 5mg

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Delivery expected until 4/20/2023

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