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Tulobuterol-d9 (hydrochloride)

Tulobuterol-d9 (hydrochloride)

Item no.	HY-B1810S-1ea
Manufacturer	MedChem Express
CASRN	1325559-14-5
Amount	1 ea
Quantity options	10 mg 1 ea 1 mg 2500 ug 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.0
Citations	[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. \|[2]Yamaya M, et al. Tulobuterol inhibits rhinovirus infection in primary cultures of human tracheal epithelial cells. Physiol Rep. 2013 Aug;1(3):e00041.;Shindoh C, et al. Tulobuterol patch maintains diaphragm muscle contractility for over twenty-four hours in a mouse model of sepsis. Tohoku J Exp Med. 2009 Aug;218(4):271-8.
Smiles	[2H]C(C(NCC(O)C1=CC=CC=C1Cl)(C([2H])([2H])[2H])C([2H])([2H])[2H])([2H])[2H].[H]Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	C-78-D9
Shipping Condition	Cool pack
Available
Manufacturer - Type	Isotope-Labeled Compounds
Manufacturer - Targets	Adrenergic Receptor; Isotope-Labeled Compounds
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, sealed storage, away from moisture)
Molecular Weight	273.25
Product Description	Tulobuterol-d9 (hydrochloride) is the deuterium labeled Tulobuterol. Tulobuterol (C-78 free base) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol is also a sympathomimetic agent used as a transdermal patch, and increases normal diaphragm muscle strength[1].
Manufacturer - Research Area	Inflammation/Immunology; Endocrinology
Solubility	H2O: 100 mg/mL (ultrasonic; warming)
Manufacturer - Pathway	GPCR/G Protein; Neuronal Signaling; Others
Clinical information	No Development Reported

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