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Levodropropizine

Levodropropizine

Item no.	HY-B1895-1g
Manufacturer	MedChem Express
CASRN	99291-25-5
Amount	1 g
Quantity options	100 mg 10mM/1mL 1 g 500 mg 50 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.71
Formula	C13H20N2O2
Citations	[1]Zanasi A, et al. Levodropropizine for treating cough in adult and children: a meta-analysis of published studies. Multidiscip Respir Med. 2015 May 31;10(1):19. [2]Luo YL, et al. Effects of four antitussives on airway neurogenic inflammation in a guinea pig model of chronic cough induced by cigarette smoke exposure. Inflamm Res. 2013 Dec;62(12):1053-61. [3]Erdogan MA, et al. Levodropropizine suppresses seizure activity in rats with pentylenetetrazol-induced epilepsy. Epilepsy Res. 2019 Feb;150:32-37. [4]Yamawaki I, et al. Levodropropizine reduces capsaicin- and substance P-induced plasma extravasation in the rat trachea. Eur J Pharmacol. 1993 Oct 12;243(1):1-6.
Smiles	OC[C@@H](O)CN1CCN(C2=CC=CC=C2)CC1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	(S)-(-)-Dropropizine; DF-526
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Histamine Receptor
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	236.31
Product Description	Levodropropizine (DF-526) is an orally active histamine receptor inhibitor, Levodropropizine is an effective and very well tolerated peripheral antitussive agent[1].
Manufacturer - Research Area	Endocrinology; Inflammation/Immunology; Neurological Disease
Solubility	DMSO : ≥ 50 mg/mL\|H2O : 10 mg/mL (ultrasonic)
Manufacturer - Pathway	GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Clinical information	Launched

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HY-B1895-1g-safety-datasheet.pdf