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Puerarin

Puerarin

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	25mg
Item no.	HY-N0145-25mg
CASRN	3681-99-0
Available
Product Description	Puerarin, an isoflavone extracted from Radix puerariae, is a 5-HT2C receptor antagonist.
StorageTemperature	Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications	COVID-19-immunoregulation
Formula	C21H20O9
References	[1].Hu W, et al. Puerarin inhibits iNOS, COX-2 and CRP expression via suppression of NF-κB activation in LPS-induced RAW264.7 macrophage cells. Pharmacol Rep. 2011; 63(3):781-9. \| [2].Zhang H, et al. Puerarin: a novel antagonist to inward rectifier potassium channel (IK1). Mol Cell Biochem. 2011 Jun; 352(1-2):117-23. \| [3].Zhao L, et al. Protective Effects of Genistein and Puerarin against Chronic Alcohol-Induced Liver Injury in Mice via Antioxidant, Anti-inflammatory, and Anti-apoptotic Mechanisms. J Agric Food Chem. 2016 Sep 28; 64(38):7291-7. \| [4].Pan X, et al. Effect of Puerarin on Expression of ICAM-1 and TNF-α in Kidneys of Diabetic Rats. Med Sci Monit. 2015 Jul 23; 21:2134-40.
MolecularWeight	416.38
Research Area	Inflammation/Immunology; Cancer
Solubility	DMSO : 50 mg/mL (120.08 mM; Need ultrasonic)
Target	5-HT Receptor
Isoform	5-HT2C Receptor
Pathway	GPCR/G Protein; Neuronal Signaling

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Amount: 25mg

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Delivery expected until 4/20/2023

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