« Back
Home /
Mangiferin

Mangiferin

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	5mg
Item no.	HY-N0290-5mg
CASRN	4773-96-0
Available
Product Description	Mangiferin is a Nrf2 activator. Mangiferin suppresses nuclear translocation of the NF-κB subunits p65 and p50. Mangiferin exhibits antioxidant, antidiabetic, antihyperuricemic, antiviral, anticancer and antiinflammatory activities.
StorageTemperature	Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications	Cancer-programmed cell death
Formula	C19H18O11
References	[1].Zhang BP, et al. Mangiferin activates Nrf2-antioxidant response element signaling without reducing the sensitivity to etoposide of human myeloid leukemia cells in vitro. Acta Pharmacol Sin. 2014 Feb; 35(2):257-66. \| [2].Dilshara MG, et al. Mangiferin inhibits tumor necrosis factor-α-induced matrix metalloproteinase-9 expression and cellular invasion by suppressing nuclear factor-κB activity. BMB Rep. 2015 Oct; 48(10):559-64.
MolecularWeight	422.34
Research Area	Cancer
Solubility	DMSO : 31.25 mg/mL (73.99 mM; ultrasonic and warming and heat to 80°C)
Target	NF-κB; Keap1-Nrf2; Apoptosis
Isoform	p65; p50; Nrf2
Pathway	NF-κB; Apoptosis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 5mg

available

Delivery expected until 4/13/2023

Compare

Add to wishlist

Recommend by mail

Request delivery time

Ask a technical question