Comparison

Glabridin European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 100mg
Item no. HY-N0393-100mg
CASRN 59870-68-7
Available
Product Description
Glabridin is a natural isoflavan from Glycyrrhiza uralensis, binds to and activates PPARγ, with an EC50 of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic, cardiovascular protective, neuroprotective and radical scavenging activities.
StorageTemperature
Powder -20°C 3 years; In solvent -80°C 6 months, -20°C 1 month
Applications
Cancer-programmed cell death
Formula
C20H20O4
References
[1].Rebhun JF, et al. Identification of glabridin as a bioactive compound in licorice (Glycyrrhiza glabra L.) extract that activates human peroxisome proliferator-activated receptor gamma (PPARγ). Fitoterapia. 2015 Oct; 106:55-61. | [2].Chen CT, et al. Glabridin induces apoptosis and cell cycle arrest in oral cancer cells through the JNK1/2 signaling pathway. Environ Toxicol. 2018 Jun; 33(6):679-685. | [3].El-Ashmawy NE, et al. Downregulation of iNOS and elevation of cAMP mediate the anti-inflammatory effect of glabridin in rats with ulcerative colitis. Inflammopharmacology. 2018 Apr; 26(2):551-559.
MolecularWeight
324.37
Research Area
Cancer; Infection; Inflammation/Immunology
Solubility
DMSO : 25 mg/mL (77.07 mM; Need ultrasonic)
Target
PPAR; Reactive Oxygen Species; Bacterial
Isoform
PPARγ
Pathway
Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Anti-infection

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 100mg
Available: In stock
available

Delivery expected until 4/6/2023 

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