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Picroside I

Picroside I

Item no.	HY-N0407-10mg
Manufacturer	MedChem Express
CASRN	27409-30-9
Amount	10 mg
Quantity options	10 mM/1 mL 10 mg 20 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.48
Citations	[2]Sen Zhang, et al. Picroside I inhibits asthma phenotypes by regulating Tbet/GATA-3 ratio and Th1/Th2 balance in a murine model of asthma. Tropical Journal of Pharmaceutical Research September 2018; 17 (9): 1777-1782.\|[1]Ganeshkumar Y, et al. Picroside I and Picroside II from Tissue Cultures of <i>Picrorhiza kurroa</i>. Pharmacognosy Res. 2017 Dec;9(Suppl 1):S53-S56.
Smiles	OC[C@]12[C@@H](O2)[C@@H](O)[C@@]3([H])[C@]1([H])[C@H](O[C@]4([H])O[C@H](COC(/C=C/C5=CC=CC=C5)=O)[C@@H](O)[C@H](O)[C@H]4O)OC=C3
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	6'-Cinnamoylcatalpol
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	STAT
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	492.47
Product Description	Picroside I is the major ingredient of Picrorhiza scrophulariiflora. Picrorhiza scrophulariiflora is a high value medicinal herb due to rich source of hepatoprotective metabolites, Picroside-I and Picroside-II[1]. Picroside I is a promising agent for the management of asthma. Picroside I reduces the inflammation significantly at its higher dose. Picroside I also downregulates pSTAT6 and GATA3 expressions. Picroside I dose-dependently increases the serum levels of IFN-γ[2].
Manufacturer - Research Area	Inflammation/Immunology
Solubility	DMSO: 250 mg/mL (ultrasonic)\|H2O: 116.67 mg/mL (ultrasonic)
Manufacturer - Pathway	JAK/STAT Signaling; Stem Cell/Wnt
Isoform	STAT6
Clinical information	No Development Reported

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HY-N0407-10mg-safety-datasheet.pdf