Comparison

Chicoric acid European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 10mM*1mL
Item no. HY-N0457-10mM*1mL
CASRN 6537-80-0
Available
Product Description
Chicoric acid (Cichoric acid), an orally active dicaffeyltartaric acid, induces reactive oxygen species (ROS) generation. Chicoric acid inhibits cell viability and induces mitochondria-dependent apoptosis in 3T3-L1 preadipocytes through ROS-mediated PI3K/Akt and MAPK signaling pathways. Chicoric acid increases glucose uptake, improves insulin resistance, and attenuates glucosamine-induced inflammation. Chicoric acid has antidiabetic properties and antioxidant, anti-inflammatory effects.
StorageTemperature
Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Formula
C22H18O12
References
[1].Haifang Xiao, et al. Chicoric acid induces apoptosis in 3T3-L1 preadipocytes through ROS-mediated PI3K/Akt and MAPK signaling pathways. J Agric Food Chem. 2013 Feb 20; 61(7):1509-20. | [2].Di Zhu, et al. Cichoric Acid Reverses Insulin Resistance and Suppresses Inflammatory Responses in the Glucosamine-Induced HepG2 Cells. J Agric Food Chem. 2015 Dec 30; 63(51):10903-13. | [3].Di Zhu, et al. Cichoric acid improved hyperglycaemia and restored muscle injury via activating antioxidant response in MLD-STZ-induced diabetic mice. Food Chem Toxicol. 2017 Sep; 107(Pt A):138-149.
MolecularWeight
474.37
Research Area
Metabolic Disease; Inflammation/Immunology
Solubility
H2O : 100 mg/mL (210.81 mM; Need ultrasonic) | DMSO : 1 mg/mL (2.11 mM; Need ultrasonic)
Target
Reactive Oxygen Species; Apoptosis
Pathway
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Apoptosis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 10mM*1mL
Available: In stock
available

Delivery expected until 4/13/2023 

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