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Ginkgolide B

Ginkgolide B

Item no.	HY-N0784-25mg
Manufacturer	MedChem Express
CASRN	15291-77-7
Amount	25 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 25 mg 50 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.96
Formula	C20H24O10
Citations	[1]Tao Zhou, et al. Ginkgolide B protects human umbilical vein endothelial cells against xenobiotic injuries via PXR activation. Acta Pharmacol Sin. 2016 Feb;37(2):177-86. [2]Pei-Dong Zheng, et al. Ginkgolide B promotes the proliferation and differentiation of neural stem cells following cerebral ischemia/reperfusion injury, both in vivo and in vitro. Neural Regen Res. 2018 Jul;13(7):1204-1211.
Smiles	O[C@@H]1C(C2([C@H]3O)[C@](OC3=O)([H])O4)([C@@](O5)([H])C[C@H]2C(C)(C)C)C4(C5=O)[C@@](O)([C@@H]6C)[C@@]1([H])OC6=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	BN-52021
Shipping condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Apoptosis; Platelet-activating Factor Receptor (PAFR)
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	424.40
Product Description	Ginkgolide B (BN-52021), a terpene lactone, is a potent platelet activating factor antagonist. Ginkgolide B protects endothelial cells via the activation of PXR from injuries induced by xeno- and endobiotics. Ginkgolide B can pass through the brain-blood barrier. Ginkgolide B has anti-oxidant, anti-inflammatory, anti-tumor, and anti-apoptotic activity. Ginkgolide B has marked neuroprotective effects against ischemia-induced impairments[1][2].
Manufacturer - Research Area	Cancer; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Solubility	DMSO : ≥ 100 mg/mL
Manufacturer - Pathway	Apoptosis; GPCR/G Protein
Clinical information	No Development Reported

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HY-N0784-25mg-safety-datasheet.pdf