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Vomicine

Vomicine

Item no.	HY-N2616-5mg
Manufacturer	MedChem Express
CASRN	125-15-5
Amount	5 mg
Quantity options	10 mg 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.77
Citations	[1]Bhati R, et al. <i>Strychnos nux-vomica</i> seeds: Pharmacognostical standardization, extraction, and antidiabetic activity. J Ayurveda Integr Med. 2012 Apr;3(2):80-4.\|[2]Zhan Y, et al., Semen Strychni Pulveratum and vomicine alleviate neuroinflammation in amyotrophic lateral sclerosis through cGAS-STING-TBK1 pathway. J Ethnopharmacol. 2025 Jan 10;336:118741.
Smiles	O=C1[C@@]23[C@](N4C5=C(O)C=CC=C35)([H])[C@@]6([H])[C@@](C(CN(C)CC2)=CCO[C@@]6([H])CC4=O)([H])C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	125-15-5
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	STING
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture and light)
Molecular Weight	380.44
Product Description	Vomicine modulates cGAS-STING-TBK1 signaling pathway, and exhibits anti-inflammatory activity. Vomicine is an alkaloid that can be isolated from Strychnos nux-vomica seeds[1][2].
Manufacturer - Research Area	Inflammation/Immunology
Solubility	DMSO: 10 mg/mL (ultrasonic; warming; heat to 60°C)\|H2O: < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Immunology/Inflammation
Clinical information	No Development Reported

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HY-N2616-5mg-safety-datasheet.pdf