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Triacsin C

Triacsin C

Item no.	HY-N6707-1mg
Manufacturer	MedChem Express
CASRN	76896-80-5
Amount	1 mg
Quantity options	100 ug 1 mg 500 ug
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.08
Citations	[1]Dechandt CRP, et al. Triacsin C reduces lipid droplet formation and induces mitochondrial biogenesis in primary rat hepatocytes. J Bioenerg Biomembr. 2017 Oct;49(5):399-411.\|[2]Kim Y, et al. Novel triacsin C analogs as potential antivirals against rotavirus infections. Eur J Med Chem. 2012 Apr;50:311-8.\|[3]Guo F, et al. Amelioration of Cryptosporidium parvum infection in vitro and in vivo by targeting parasite fatty acyl-coenzyme A synthetases. J Infect Dis. 2014 Apr 15;209(8):1279-87. \|[4]Matsuda D, et al. Anti-atherosclerotic activity of triacsin C, an acyl-CoA synthetase inhibitor. J Antibiot (Tokyo). 2008 May;61(5):318-21.
Smiles	CCC/C=C/C/C=C/C=C/C=N/NN=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	WS 1228A,FR 900190
Shipping Condition	Cool pack
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	COVID-19-anti-virus
Manufacturer - Targets	Parasite
Shipping Temperature	Blue Ice
Storage Conditions	-20°C, 3 years (Powder)
Molecular Weight	207.27
Product Description	Triacsin C (WS 1228A), is an orally active and intracellular long-chain acyl-CoA synthetases (ACSL) inhibitor, which can be isolated from Streptomyces aureofaciens. Triacsin C inhibits TAG accumulation into lipid droplets (LD) by suppressing ACSL activity[1]. Triacsin C exhibits highly inhibitory effect against rotavirus replication[2].
Manufacturer - Research Area	Infection; Cardiovascular Disease
Solubility	DMSO: 5 mg/mL (ultrasonic; warming)
Manufacturer - Pathway	Anti-infection
Clinical information	No Development Reported

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HY-N6707-1mg-safety-datasheet.pdf