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Juglone

Juglone

Item no.	HY-N6949-5mg
Manufacturer	MedChem Express
CASRN	481-39-0
Amount	5 mg
Quantity options	100 mg 10 mg 20 mg 25 mg 50 mg 5 mg
Category	Food Safety Allergenes Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.88
Citations	[1]Zmantar T, et al. Use of juglone as antibacterial and potential efflux pump inhibitors in Staphylococcus aureus isolated from the oral cavity. Microb Pathog. 2016 Dec;101:44-49.\|[2]Ji YB, et al. Juglone-induced apoptosis in human gastric cancer SGC-7901 cells via the mitochondrial pathway. Exp Toxicol Pathol. 2011 Jan;63(1-2):69-78.\|[3]Peng X, et al. Juglone prevents metabolic endotoxemia-induced hepatitis and neuroinflammation via suppressing TLR4/NF-κB signaling pathway in high-fat diet rats. Biochem Biophys Res Commun. 2015 Jul 3;462(3):245-50.
Smiles	O=C(C1=C2C=CC=C1O)C=CC2=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	5-Hydroxy-1,4-naphthalenedione
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Apoptosis; Bacterial; NF-κB; Toll-like Receptor (TLR)
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	174.16
Product Description	Juglone (5-hydroxy-1, 4-naphthalenedione) is a yellow dye that can be extracted from Juglans regia. Juglone induces apoptosis through the mitochondrial pathway. Juglone has antibacterial and antitumor activity[1][2][3].
Manufacturer - Research Area	Cancer; Infection; Inflammation/Immunology
Solubility	DMSO: 50 mg/mL (ultrasonic)\|Ethanol: ≥ 3.33 mg/mL
Manufacturer - Pathway	Anti-infection; Apoptosis; Immunology/Inflammation; NF-κB
Clinical information	Phase 3

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-N6949-5mg-safety-datasheet.pdf