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6-Benzoylheteratisine

6-Benzoylheteratisine

Item no.	HY-N9404-1ea
Manufacturer	MedChem Express
CASRN	99759-48-5
Amount	1 ea
Quantity options	10 mg 1 ea 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.66
Citations	[1]Gutser UT, et al. The alkaloid 6-benzoylheteratisine inhibits voltage-gated Na+ channels in rat brain synaptosomes. Neuropharmacology. 1998 Sep;37(9):1139-46.\|[2]Ameri A. Effects of the alkaloids 6-benzoylheteratisine and heteratisine on neuronal activity in rat hippocampal slices. Neuropharmacology. 1997 Aug;36(8):1039-46.
Smiles	CO[C@@H]1[C@]23[C@]4([H])[C@@H]([C@@]([C@@]5([C@]6([H])[C@@]3([H])C[C@H](CC5)OC6=O)O)([H])[C@@]2([H])N(C[C@@]4(CC1)C)CC)OC(C7=CC=CC=C7)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Sodium Channel
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	495.61
Product Description	6-Benzoylheteratisine is an Aconitum alkaloid with potential neuroprotective activity. 6-Benzoylheteratisine can antagonize tetrodotoxin, inhibit the increase of [Na+]i, [Ca2+]i and glutamate release, and block sodium channels. 6-Benzoylheteratisine has an inhibitory effect on the neuronal activity underlying epileptiform burst discharge[1][2].
Manufacturer - Research Area	Neurological Disease
Solubility	10 mM in DMSO
Manufacturer - Pathway	Membrane Transporter/Ion Channel
Clinical information	No Development Reported

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HY-N9404-1ea-safety-datasheet.pdf