CALP3

Item no.	HY-P1075-10mg
Manufacturer	MedChem Express
CASRN	261969-05-5
Amount	10 mg
Quantity options	10 mg 1 mg 25 mg 50 mg 5 mg
Category	Peptides & Proteins Peptides
Type	Peptides
Specific against	other
Purity	98.57
Citations	[1]Manion MK, et al. A new type of Ca(2+) channel blocker that targets Ca(2+) sensors and prevents Ca(2+)-mediated apoptosis. FASEB J. 2000 Jul;14(10):1297-306.\|[2]Ferdek PE, et al. BH3 mimetic-elicited Ca2+ signals in pancreatic acinar cells are dependent on Bax and can be reduced by Ca<sup>2+</sup>-like peptides. Cell Death Dis. 2017 Mar 2;8(3):e2640.
Smiles	O=C([C@@H](N)C(C)C)N[C@@H](CCCCN)C(N[C@H](C(NCC(N[C@@H](C(C)C)C(NCC(N[C@H](C(N[C@H](C(O)=O)CCCCN)=O)CC1=CC=CC=C1)=O)=O)=O)=O)CC2=CC=CC=C2)=O
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	261969-05-5
Similar products	261969-05-5
Shipping Condition	Cool pack
Available
Manufacturer - Type	Peptides
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Calcium Channel
Shipping Temperature	Blue Ice
Storage Conditions	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Molecular Weight	881.07
Product Description	CALP3, a Ca2+-like peptide, is a potent Ca2+ channel blocker that activates EF hand motifs of Ca2+-binding proteins. CALP3 can functionally mimic increased [Ca2+]i by modulating the activity of Calmodulin (CaM), Ca2+ channels and pumps. CALP3 has the potential in controlling apoptosis in diseases such as AIDS or neuronal loss due to ischemia[1][2].
Manufacturer - Research Area	Cancer; Neurological Disease
Solubility	DMSO: 12.5 mg/mL (ultrasonic)
Manufacturer - Pathway	Membrane Transporter/Ion Channel; Neuronal Signaling
Isoform	Calcium Channel
Clinical information	No Development Reported

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HY-P1075-10mg-safety-datasheet.pdf