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Angiotensin III, human, mouse

Angiotensin III, human, mouse

Item no.	HY-P1540-50mg
Manufacturer	MedChem Express
CASRN	13602-53-4
Amount	50 mg
Quantity options	100 mg 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	98.27
Citations	[1]Bosnyak S, et al. Relative affinity of angiotensin peptides and novel ligands at AT1 and AT2 receptors. Clin Sci (Lond). 2011 Oct;121(7):297-303.\|[2]Kemp BA, et al. Intrarenal angiotensin III is the predominant agonist for proximal tubule angiotensin type 2 receptors. Hypertension. 2012 Aug;60(2):387-95.\|[3]Gao J, et al. A new strategy for treating hypertension by blocking the activity of the brain renin-angiotensin system with aminopeptidase A inhibitors. Clin Sci (Lond). 2014 Aug;127(3):135-48.
Smiles	O=C(N[C@@H](C(C)C)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC2=CNC=N2)C(N3[C@@H](CCC3)C(N[C@@H](CC4=CC=CC=C4)C(O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Type	Peptides
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Angiotensin Receptor
Shipping Temperature	Blue Ice
Storage Conditions	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Molecular Weight	931.09
Product Description	Angiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT2R) agonist, with IC50s of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively.
Manufacturer - Research Area	Cardiovascular Disease; Endocrinology
Solubility	H2O: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	GPCR/G Protein
Isoform	AT2 Receptor
Clinical information	No Development Reported

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HY-P1540-50mg-safety-datasheet.pdf