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C-Reactive Protein (CRP) (174-185)

C-Reactive Protein (CRP) (174-185)

Item no.	HY-P1823-10mg
Manufacturer	MedChem Express
CASRN	147516-85-6
Amount	10 mg
Quantity options	100 mg 10 mg 1 ea 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.88
Citations	[1]Singh SK, et al. Complement Activation by C-Reactive Protein Is Critical for Protection of Mice Against Pneumococcal Infection. Front Immunol. 2020 Aug 13;11:1812. \|[2]Devaraj S, et al. C-reactive protein stimulates superoxide anion release and tissue factor activity in vivo. Atherosclerosis. 2009 Mar;203(1):67-74. \|[3]Chen JY, et al. C-reactive protein derived from perivascular adipose tissue accelerates injury-induced neointimal hyperplasia. J Transl Med. 2020 Feb 11;18(1):68. \|[4]Tang Y, et al. C-reactive protein promotes acute kidney injury by impairing G1/S-dependent tubular epithelium cell regeneration. Clin Sci (Lond). 2014 May;126(9):645-59. \|[5]Yan X, et al. C-reactive protein promotes tongue squamous cell carcinoma chemoresistance by inhibiting the activation of caspase-3/9 via the CD64/AKT/mTOR pathway. Hum Cell. 2021 Sep;34(5):1424-1433. \|[6]Ansar W, et al. C-reactive protein and the biology of disease. Immunol Res. 2013 May;56(1):131-42.
Smiles	CC(C)C[C@@H](C(O)=O)NC([C@H](C(C)C)NC([C@H](CC(N)=O)NC([C@H]1N(C([C@H](CO)NC([C@H](CC2=CC=CC=C2)NC([C@H]3N(C(CNC(CNC([C@H](CC(C)C)NC([C@H](CC4=CC=C(O)C=C4)NC([C@H]([C@@H](C)CC)N)=O)=O)=O)=O)=O)CCC3)=O)=O)=O)CCC1)=O)=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Type	Peptides
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Akt; Caspase; mTOR
Shipping Temperature	Blue Ice
Storage Conditions	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Molecular Weight	1276.48
Product Description	C-Reactive Protein (CRP) is an anti-pneumococcal plasma protein that can serve as an inflammatory marker. C-Reactive protein can protect mice from pneumococcal infection by activating complement. C-Reactive protein can inhibit the activation of caspase-3/9 through the CD64/AKT/mTOR pathway, thereby promoting chemotherapy resistance in mice with tongue squamous cell carcinoma[1][5].
Manufacturer - Research Area	Cancer; Infection; Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Solubility	H2O
Manufacturer - Pathway	Apoptosis; PI3K/Akt/mTOR
Clinical information	No Development Reported

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HY-P1823-10mg-safety-datasheet.pdf