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Bivalirudin

Bivalirudin

Item no.	HY-P1929-1ea
Manufacturer	MedChem Express
CASRN	128270-60-0
Amount	1 ea
Quantity options	100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.97
Citations	[1]André P, et al. Anticoagulants (thrombin inhibitors) and aspirin synergize with P2Y12 receptor antagonism in thrombosis.Circulation. 2003 Nov 25;108(21):2697-703.\|[2]Ye H, et al. Bivalirudin Attenuates Thrombin-Induced Endothelial Hyperpermeability via S1P/S1PR2 Category: Original Articles. Front Pharmacol. 2021 Aug 3;12:721200.\|[3]Zhuang S, et al. Bivalirudin exerts antiviral activity against respiratory syncytial virus-induced lung infections in neonatal mice. Acta Pharm. 2022 Apr 13;72(3):415-425.\|[4]Warkentin TE, et al. Bivalirudin: a review. Expert Opin Pharmacother. 2005 Jul;6(8):1349-71. Compos B Eng. 2024 Aug 15.\|Allergy. 2022 Jan 7.\|Antiviral Res. 2023 Apr 17;105606.\|Compos B Eng. 1 April 2022, 109702.\|Elife. 2022 Mar 23:11:e77444.\|Int J Auto Tech-Jpn. 2020 Jan.\|J Am Soc Mass Spectrom. 2020 Jul 5.\|J Clin Pathol. 2019 Dec;72(12):817-824.
Smiles	O=C([C@H]1N(CCC1)C([C@H](CCCNC(N)=N)NC([C@H]2N(CCC2)C([C@H](N)CC3=CC=CC=C3)=O)=O)=O)NCC(NCC(NCC(NCC(N[C@@H](CC(N)=O)C(NCC(N[C@@H](CC(O)=O)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N5[C@@H](CCC5)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@H](C(O)=O)CC(C)C)=O)CC6=CC=C(C=C6)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Type	Peptides
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Interleukin Related; RSV; Thrombin
Shipping Temperature	Blue Ice
Storage Conditions	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Molecular Weight	2180.29
Product Description	Bivalirudin, a hirudin analog and anticoagulant, is a direct thrombin inhibitor. Bivalirudin inhibits thrombin-mediated fibrinogen cleavage, coagulation factor activation, and platelet activation by reversibly binding to thrombin. In addition, Bivalirudin also has certain effects of anti-virus, anti-inflammation, and vascular endothelial barrier function protection. Bivalirudin can be used for the research of thrombotic diseases and others[1][2][3][4].
Manufacturer - Research Area	Infection; Inflammation/Immunology; Cardiovascular Disease
Solubility	H2O: 10 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease
Isoform	IL-5; IL-6
Clinical information	Launched

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-P1929-1ea-safety-datasheet.pdf