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Aureobasidin A

Aureobasidin A

Item no.	HY-P1975-1mg
Manufacturer	MedChem Express
CASRN	127785-64-2
Amount	1 mg
Quantity options	10 mg 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.36
Citations	[1]Zheng L, et al. Chromosome 1 trisomy confers resistance to aureobasidin A in Candida albicans. Front Microbiol. 2023 Mar 17;14:1128160.\|[2]Alqaisi AQI, et al. The antifungal Aureobasidin A and an analogue are active against the protozoan parasite Toxoplasma gondii but do not inhibit sphingolipid biosynthesis. Parasitology. 2018 Feb;145(2):148-155.\|[3]Takesako K, et al. Biological properties of aureobasidin A, a cyclic depsipeptide antifungal antibiotic. J Antibiot (Tokyo). 1993 Sep;46(9):1414-20.
Smiles	O=C([C@@H](N(C([C@@H](NC([C@@H](N(C([C@@](OC1=O)([H])[C@H](C)CC)=O)C)C(C)C)=O)CC2=CC=CC=C2)=O)C)CC3=CC=CC=C3)N(CCC4)[C@]4([H])C(N[C@@](C(N([C@H](C(N[C@H](C(N([C@H]1C(C)(O)C)C)=O)CC(C)C)=O)C(C)C)C)=O)([H])[C@H](C)CC)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Basifungin
Shipping Condition	Cool pack
Available
Manufacturer - Type	Peptides
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Antibiotic; Fungal; Parasite
Shipping Temperature	Blue Ice
Storage Conditions	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Molecular Weight	1101.42
Product Description	Aureobasidin A (Basifungin) is a cyclic peptide antibiotic with oral activity. Aureobasidin A is an inhibitor of inositol phosphorylated ceramide synthetase AUR1. Aureobasidin A has antifungal and antiparasitic activity[1][2][3].
Manufacturer - Research Area	Infection; Inflammation/Immunology
Solubility	DMSO: 50 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection
Clinical information	No Development Reported

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HY-P1975-1mg-safety-datasheet.pdf