CYP21A2, Human (P.pastoris, His)

Recombinant Proteins

Stored at -20°C for 2 years

CYP21A2 Protein, a cytochrome P450 monooxygenase, crucially hydroxylates progesterone and 17alpha-hydroxyprogesterone at C-21, yielding vital intermediates for mineralocorticoid and glucocorticoid biosynthesis in adrenal steroidogenesis. This enzymatic process involves molecular oxygen, with NADPH providing essential electrons via cytochrome P450 reductase (CPR). CYP21A2 plays a pivotal role in regulating adrenal cortex hormone production. CYP21A2 Protein, Human (P.pastoris, His) is the recombinant human-derived CYP21A2 protein, expressed by P. pastoris , with N-6*His labeled tag.