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IFN-alpha 2/IFNA2, Mouse (HEK293, Fc)

IFN-alpha 2/IFNA2, Mouse (HEK293, Fc)

Item no.	HY-P73248-20ug
Manufacturer	MedChem Express
Amount	20 ug
Quantity options	100 ug 10 ug 20 ug 50 ug 5 ug
Category	Inhibitors & Compound Libraries Small Molecules
Type	Peptides
Specific against	other
Purity	97.50
Dry ice	Yes
Sequence	CDLPHTYNLR NKRALKVLAQ MRRLPFLSCL KDRQDFGFPL EKVDNQQIQK AQAIPVLRDL TQQTLNLFTS KASSAAWNAT LLDSFCNDLH QQLNDLQTCL MQQVGVQEPP LTQEDALLAV RKYFHRITVY LREKKHSPCA WEVVRAEVWR ALSSSVNLLP RLSEEKE
Citations	[1]Watanabe H, et al. Detailed structure of mouse interferon α2 and its interaction with Sortilin. J Biochem. 2021 Oct 11;170(2):265-273. [2]Abraham S, et al. Gene therapy with plasmids encoding IFN-β or IFN-α14 confers long-term resistance to HIV-1 in humanized mice. Oncotarget. 2016 Nov 29;7(48):78412-78420. [3]Zhang SY, et al. Inborn errors of interferon (IFN)-mediated immunity in humans: insights into the respective roles of IFN-alpha/beta, IFN-gamma, and IFN-lambda in host defense. Immunol Rev. 2008 Dec;226:29-40. [4]Sutter K, et al. Interferon α subtypes in HIV infection. Cytokine Growth Factor Rev. 2018 Apr;40:13-18. [5]Gull I, et al. Heterologous expression, immunochemical and computational analysis of recombinant human interferon alpha 2b. Springerplus. 2013 Jun 15;2(1):264. [6]Paul F, et al. IFNA2: The prototypic human alpha interferon. Gene. 2015 Aug 10;567(2):132-7.
Smiles	CDLPHTYNLR NKRALKVLAQ MRRLPFLSCL KDRQDFGFPL EKVDNQQIQK AQAIPVLRDL TQQTLNLFTS KASSAAWNAT LLDSFCNDLH QQLNDLQTCL MQQVGVQEPP LTQEDALLAV RKYFHRITVY LREKKHSPCA WEVVRAEVWR ALSSSVNLLP RLSEEKE
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IFN-alpha 2/IFNA2 Protein, Mouse (HEK293, Fc),Mouse,HEK293
Shipping condition	Dry ice
Available
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Dry Ice
Storage Conditions	Stored at -80°C for 1 year
Molecular Weight	Approximately 52 kDa
Product Description	IFN-alpha 2 (IFNA2), belongs to type I interferon family, is a protein secreted by cells infected by a virus and acting on other cells to inhibit viral infection[1]. IFN-alpha 2 exerts cytotoxic activity against CD8+ T cells and induces CD4+ T cell depletion[3]. IFN-alpha 2/IFNA2 Protein, Mouse (HEK293, Fc) contains 167 a.a. (C24-E190), is produced in HEK293 cells with a N-terminal hFc-tag.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-P73248-20ug-safety-datasheet.pdf