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Nicastrin, Human (HEK293, His)

Nicastrin, Human (HEK293, His)

Item no.	HY-P74698-10ug
Manufacturer	MedChem Express
Amount	10 ug
Quantity options	100 ug 10 ug 20 ug 50 ug 5 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Purity	98.0
Sequence	NSVERKIYIP LNKTAPCVRL LNATHQIGCQ SSISGDTGVI HVVEKEEDLQ WVLTDGPNPP YMVLLESKHF TRDLMEKLKG RTSRIAGLAV SLTKPSPASG FSPSVQCPND GFGVYSNSYG PEFAHCREIQ WNSLGNGLAY EDFSFPIFLL EDENETKVIK QCYQDHNLSQ NGSAPTFPLC AMQLFSHMHA VISTATCMRR SSIQSTFSIN PEIVCDPLSD YNVWSMLKPI NT
Smiles	NSVERKIYIP LNKTAPCVRL LNATHQIGCQ SSISGDTGVI HVVEKEEDLQ WVLTDGPNPP YMVLLESKHF TRDLMEKLKG RTSRIAGLAV SLTKPSPASG FSPSVQCPND GFGVYSNSYG PEFAHCREIQ WNSLGNGLAY EDFSFPIFLL EDENETKVIK QCYQDHNLSQ NGSAPTFPLC AMQLFSHMHA VISTATCMRR SSIQSTFSIN PEIVCDPLSD YNVWSMLKPI NTTGTLKPDD RVVVAATRLD SRSFFWNVAP GAESAVASFV TQLAAAEALQ KAPDVTTLPR NVMFVFFQGE TFDYIGSSRM VYDMEKGKFP VQLENVDSFV ELGQVALRTS LELWMHTDPV SQKNESVRNQ VEDLLATLEK SGAGVPAVIL RRPNQSQPLP PSSLQRFLRA RNISGVVLAD HSGAFHNKYY QSIYDTAENI NVSYPEWLSP EEDLNFVTDT AKALADVATV LGRALYELAG GTNFSDTVQA DPQTVTRLLY GFLIKANNSW FQSILRQDLR SYLGDGPLQH YIAVSSPTNT TYVVQYALAN LTGTVVNLTR EQCQDPSKVP SENKDLYEYS WVQGPLHSNE TDRLPRCVRS TARLARALSP AFELSQWSST EYSTWTESRW KDIRARIFLI ASKELE
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Nicastrin Protein,Human (HEK293,His),Human,HEK293
Shipping Condition	Cool pack
Available
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Blue Ice
Storage Conditions	Stored at -20°C for 2 years
Molecular Weight	Approximately 105-125 kDa
Product Description	Nicastrin Protein, a crucial gamma-secretase complex subunit, catalyzes intramembrane cleavage of Notch receptors and APP.Operating in Notch and Wnt signaling, the complex modulates regulatory proteins and CTNNB1 levels.Collaborating with PSEN1/2, APH1A/B, and PSENEN/PEN2, Nicastrin binds to proteolytically processed C83 and C99 fragments, emphasizing its pivotal role in molecular pathways and cellular processes.Nicastrin Protein, Human (HEK293, His) is the recombinant human-derived Nicastrin protein, expressed by HEK293 , with C-His labeled tag.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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