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Nesvacumab

Nesvacumab

Item no.	HY-P99036-10mg
Manufacturer	MedChem Express
CASRN	1296818-77-3
Amount	10 mg
Quantity options	10 mg 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.11
Dry ice	Yes
Citations	[1]Kyriakos P Papadopoulos, et al. A Phase I First-in-Human Study of Nesvacumab (REGN910), a Fully Human Anti-Angiopoietin-2 (Ang2) Monoclonal Antibody, in Patients with Advanced Solid Tumors. Clin Cancer Res. 2016 Mar 15;22(6):1348-55.
Smiles	[Nesvacumab]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Dry ice
Available
Manufacturer - Type	Inhibitory Antibodies
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Tie
Shipping Temperature	Dry Ice
Storage Conditions	Store at -80°C for 2 years
Molecular Weight	(144.86 kDa)
Product Description	Nesvacumab is a fully human immunoglobulin G1 (IgG1) monoclonal antibody that specifically binds and inactivates the Tie2 receptor ligand Angiopoietin-2 (Ang2) with high affinity, but shows no binding to Ang1[1].
Manufacturer - Research Area	Inflammation/Immunology; Cardiovascular Disease; Cancer
Solubility	H2O
Manufacturer - Pathway	Protein Tyrosine Kinase/RTK
Clinical information	Phase 1

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-P99036-10mg-safety-datasheet.pdf