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Sarilumab

Sarilumab

Item no.	HY-P9916-1ea
Manufacturer	MedChem Express
Amount	1 ea
Quantity options	10 mg 1 ea 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	98.37
Dry ice	Yes
Citations	[1]McCarty D, et al. Efficacy and safety of sarilumab in patients with active rheumatoid arthritis. Ther Adv Musculoskelet Dis. 2018;10(3):61-67. [2]Xu C, et al. Population Pharmacokinetics of Sarilumab in Patients with Rheumatoid Arthritis. Clin Pharmacokinet. 2019;58(11):1455-1467.
Smiles	[Sarilumab]
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Anti-Human IL6Rα, Human Antibody
Shipping condition	Dry ice
Available
Manufacturer - Type	Inhibitory Antibodies
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Interleukin Related
Shipping Temperature	Dry Ice
Storage Conditions	Store at -80°C for 2 years
Product Description	Sarilumab (Anti-Human IL6Rα, Human Antibody) is a human immunoglobulin G1 monoclonal antibody. Sarilumab, a interleukin-6 (IL-6) receptor antagonist, binds to the IL-6 receptor with high affinity and inhibits cis and trans signaling by IL-6, resulting in reduced inflammation. Sarilumab can be used for the research of Rheumatoid arthritis[1][2].
Manufacturer - Research Area	Inflammation/Immunology; Cancer
Solubility	H2O
Manufacturer - Pathway	Immunology/Inflammation
Isoform	IL-6
Clinical information	Launched

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-P9916-1ea-safety-datasheet.pdf