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Dostarlimab

Dostarlimab

Item no.	HY-P99345-1mg
Manufacturer	MedChem Express
CASRN	2022215-59-2
Amount	1 mg
Quantity options	10 mg 1 ea 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	98.92
Dry ice	Yes
Citations	[1]Kumar S, et al. Preclinical characterization of dostarlimab, a therapeutic anti-PD-1 antibody with potent activity to enhance immune function in in vitro cellular assays and in vivo animal models. MAbs. 2021 Jan-Dec;13(1):1954136.
Smiles	[Dostarlimab]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	TSR-042
Shipping Condition	Dry ice
Available
Manufacturer - Type	Inhibitory Antibodies
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	PD-1/PD-L1
Shipping Temperature	Dry Ice
Storage Conditions	Store at -80°C for 2 years
Molecular Weight	(144.18 kDa)
Product Description	Dostarlimab (TSR-042) is a humanized anti-PD-1 monoclonal antibody. Dostarlimab binds with high affinity to human PD-1 and competitively inhibits its interaction with its ligands, PD-L1 and PD-L2, with IC50s of 1.8 and 1.5 nM, respectively[1].
Manufacturer - Research Area	Cancer
Solubility	H2O
Manufacturer - Pathway	Immunology/Inflammation
Clinical information	Launched

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HY-P99345-1mg-safety-datasheet.pdf