Comparison

CDC801 European Partner

Item no. HY-U00179-10mM
Manufacturer MedChem Express
CASRN 192819-27-5
Amount 10 mM/1 mL
Quantity options 100 mg 10 mM/1 mL 10 mg 1 ea 1 mg 20 mg 25 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 98.94
Citations [1]Man HW, et al. Discovery of (S)-N-[2-[1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl] acetamide (apremilast), a potent and orally active phosphodiesterase 4and tumor necrosis factor-alpha inhibitor. J Med Chem. 2009 Mar 26;52(6):1522-4.
Smiles NC(CC(C1=CC(OC2CCCC2)=C(OC)C=C1)N3C(C4=C(C=CC=C4)C3=O)=O)=O
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Shipping Condition Room temperature
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
Cancer-programmed cell death
Manufacturer - Targets
Phosphodiesterase (PDE); TNF Receptor
Shipping Temperature
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight
408.45
Product Description
CDC801 is a potent and orally active phosphodiesterase 4 (PDE4) and tumor necrosis factor-α (TNF-α) inhibitor with IC50 of 1.1 μM and 2.5 μM, respectively.
Manufacturer - Research Area
Cancer
Solubility
10 mM in DMSO
Manufacturer - Pathway
Apoptosis; Metabolic Enzyme/Protease
Isoform
PDE4
Clinical information
Phase 2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mM/1 mL
Available: In stock
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