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7,8-Dihydroxyflavone

7,8-Dihydroxyflavone

Item no.	HY-W013372-25mg
Manufacturer	MedChem Express
CASRN	38183-03-8
Amount	25 mg
Quantity options	10 mM/1 mL 25 mg 50 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.90
Citations	[1]Zhang Z, et al. 7,8-dihydroxyflavone prevents synaptic loss and memory deficits in a mouse model of Alzheimer's disease. Neuropsychopharmacology. 2014 Feb;39(3):638-50.
Smiles	O=C1C=C(C2=CC=CC=C2)OC3=C(O)C(O)=CC=C13
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Neuroscience-Neurodegeneration
Manufacturer - Targets	Apoptosis; Trk Receptor
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, stored under nitrogen)
Molecular Weight	254.24
Product Description	7, 8-Dihydroxyflavone is a potent and selective TrkB agonist that mimics the physiological actions of Brain-derived neurotrophic factor (BDNF). Displays therapeutic efficacy toward various neurological diseases[1].
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO: ≥ 100 mg/mL
Manufacturer - Pathway	Apoptosis; Neuronal Signaling; Protein Tyrosine Kinase/RTK
Isoform	TrkB
Clinical information	No Development Reported

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HY-W013372-25mg-safety-datasheet.pdf