« Back
Home /
(R)-3-O-Methyldopa-d3

(R)-3-O-Methyldopa-d3

Item no.	HY-W401531S-1ea
Manufacturer	MedChem Express
CASRN	1259947-39-1
Amount	1 ea
Quantity options	1 ea 1 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Citations	[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.\|[2]Asanuma M, Miyazaki I. 3-O-Methyldopa inhibits astrocyte-mediated dopaminergic neuroprotective effects of L-DOPA. BMC Neurosci. 2016 Jul 25;17(1):52.
Smiles	OC([C@H](N)CC1=CC(OC([2H])([2H])[2H])=C(C=C1)O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Isotope-Labeled Compounds
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Dopamine Receptor; Endogenous Metabolite
Shipping Temperature	Room temperature
Molecular Weight	214.23
Product Description	(R)-3-O-Methyldopa-d3 is a deuterium labeled (R)-3-O-Methyldopa, and (R)-3-O-Methyldopa is an R-enantiomer of 3-O-Methyldopa. 3-O-Methyldopa is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of L-DOPA and dopamine[1][2].
Manufacturer - Research Area	Neurological Disease
Solubility	10 mM in DMSO
Manufacturer - Pathway	GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 1 ea

available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question