« Back
Home /
Sepantronium Bromide (YM155)

Sepantronium Bromide (YM155)

Item no.	S1130-200
Manufacturer	Selleckchem
CASRN	781661-94-7
Amount	200 mg
Quantity options	10 mg 100mg 1g 10 g 10mM/1mL 200 mg 25mg 5mg 50 mg 5 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	CC1=[N+](C2=C(N1CCOC)C(=O)C3=CC=CC=C3C2=O)CC4=NC=CN=C4.[Br-]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	781661-94-7'
Available
Manufacturer - Targets	Survivin
Storage Conditions	2 years -80 in solvent
Information	Sepantronium Bromide(YM155) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0.54 nM in HeLa-SURP-luc and CHO-SV40-luc cells; does not significantly inhibit SV40 promoter activity, but is observed to slightly inhibit the interaction of Survivin with XIAP. YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells. Phase 2.
Pathway	Apoptosis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 200 mg

available

Delivery expected until 6/19/2025

Express Delivery: Save 3 days

Compare

Add to wishlist

Recommend by mail