Comparison

Tanespimycin (17-AAG) European Partner

Item no. S1141-5
Manufacturer Selleckchem
CASRN 75747-14-7
Amount 5 mg
Quantity options 100 mg 1 g 10 g 10 mM/1 mL 200 mg 25 mg 5 mg 5 g
Category
Type Inhibitors
Specific against other
Smiles CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)C)OC)OC(=O)N)C)C)O)OC
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias CP127374,NSC-330507,KOS 953
Available
Manufacturer - Targets
HSP (HSP90)
Storage Conditions
2 years -80 in solvent
Information
Tanespimycin (17-AAG, CP127374, NSC-330507, KOS 953) is a potent HSP90 inhibitor with IC50 of 5 nM in a cell-free assay, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells. Tanespimycin (17-AAG) induces apoptosis, necrosis, autophagy and mitophagy. Phase 3.
Pathway
Cytoskeletal Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 mg
Available: In stock
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