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Leucovorin (Folinic acid) Calcium Pentahydrate

Leucovorin (Folinic acid) Calcium Pentahydrate

Manufacturer	Selleckchem
Category	Food Safety Vitamines Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	50 mg
Item no.	S1236-50
CASRN	6035-45-6
eClass 6.1	30220300
eClass 9.0	32160605
Available
Description	Human lymphoid cell lines were studied for leucovorin requirements to protect from methotrexate (MTX)-induced growth suppression. Over a 72h continuous exposure leucovorin provided better protection to the cell lines LAZ-007 and RAJI than to the cell lines CCRF-CEM and MOLT-4. [1]Leucovorin is a compound similar to folic acid, which is a necessary vitamin. It has been around and in use for many decades. Leucovorin is a medication frequently used in combination with the chemotherapy drugs fluoruracil and methotrexate. Leucovorin is a chemoprotectant, not a chemotherapy drug, however, it is used in addition to these chemotherapy drugs to enhance anti cancer effects (with fluorouracil) or to help prevent or lessen side effects (with methotrexate). [2]
Molecular Weight (MW)	601, 58
Picture ChemicalStructure Description	Leucovorin Calcium Chemical Structure
Solubility (25C)	DMSO <1 mg/mL, Water 120 mg/mL, Ethanol <1 mg/mL
Storage	2 years -20CPowder, 2 weeks4Cin DMSO, 2 months-80Cin DMSO

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Amount: 50 mg

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Delivery expected until 5/2/2024