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JNJ-7706621

JNJ-7706621

Item no.	S1249-200
Manufacturer	Selleckchem
CASRN	443797-96-4
Amount	200 mg
Quantity options	1 mg 10 mg 100 mg 1 g 10 g 10 mM/1 ml 2 mg 200 mg 5 mg 50 mg 5 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	C1=CC(=C(C(=C1)F)C(=O)N2C(=NC(=N2)NC3=CC=C(C=C3)S(=O)(=O)N)N)F
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	443797-96-4'
Available
Manufacturer - Targets	CDK
Storage Conditions	2 years -80 in solvent
Information	JNJ-7706621 is a pan-CDK inhibitor with the highest potency on CDK1/2 with IC50 of 9 nM/4 nM and showing >6-fold selectivity for CDK1/2 than CDK3/4/6 in cell-free assays. It also potently inhibits Aurora A/B and has no activity on Plk1 and Wee1.
Pathway	Cell Cycle

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

S1249-200-datasheet.pdf

S1249-200-safety-datasheet.pdf