BX-795

Manufacturer	Selleckchem
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	10 mM/1 ml
Item no.	S1274-10mM
CASRN	702675-74-9
eClass 6.1	30220300
eClass 9.0	32160605
Available
Information	BX-795 is a potent and specific PDK1 inhibitor with IC50 of 6 nM, 140- and 1600-fold more selective for PDK1 than PKA and PKC in cell-free assays, respectively. Meanwhile, in comparison to GSK3β more than 100-fold selectivity observed for PDK1. BX-795 modulates autophagy via inhibiting ULK1. BX-795 also is a potent TBK1 inhibitor that blocks both TBK1 and IKKε with IC 50 values of 6 nM and 41 nM, respectively.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mM/1 ml

available

Delivery expected until 5/16/2024