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Silmitasertib (CX-4945)

Silmitasertib (CX-4945)

Item no.	S2248-1
Manufacturer	Selleckchem
CASRN	1009820-21-6
Amount	1 mg
Quantity options	1 mg 100 mg 1 g 10 g 10 mM/1 mL 2 mg 5 mg 50 mg 5 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	C1=CC(=CC(=C1)Cl)NC2=NC3=C(C=CC(=C3)C(=O)O)C4=C2C=CN=C4
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1009820-21-6'
Available
Manufacturer - Targets	Casein Kinase
Storage Conditions	2 years -80 in solvent
Information	Silmitasertib (CX-4945) is a potent and selective inhibitor of CK2 (casein kinase 2) with IC50 of 1 nM in a cell-free assay, less potent to Flt3, Pim1 and CDK1 (inactive in cell-based assay). Silmitasertib induces autophagy and promotes apoptosis. Phase 1/2.
Pathway	Metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

S2248-1-datasheet.pdf

S2248-1-safety-datasheet.pdf