Comparison

5-Aminolevulinic acid HCl European Partner

Item no. S2553-10
Manufacturer Selleckchem
CASRN 02.09.5451
Amount 10 mg
Category
Type Inhibitors
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias Levulan, ALA, Others
Similar products 5-Aminolevulinic
Available
Description
5-Aminolevulinic acid is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles, such as chlorophyll and heme. In mammals, yeast, fungi and the purple bacteria, 5-aminolevulinic acid is formed by the Shemin pathway. Then it is used in the synthesis of hemes, vitamin B12 and bacteriochlorophyll. Two molecules of 5-aminolevulinic acid are condensed to form porphobilinogen. It is the first step compound in the porphyrin synthesis. Aminolevulinic acid HCl (5-aminolevulinic acid HCl) is a prodrug that is metabolized intracellularly to form the photosensitizing molecule protoporphyrin (PpIX). When PpIX is activated by light, cytotoxic reactive oxygen species and free radicals are generated. ALA can diffuse through skin and preferentially localizes in tumors and dysplasic tissue. Subsequent exposure of PpIX-loaded tumor cells to light can destroy the tumor. [1][2]
Molecular Weight (MW)
167, 59
Picture ChemicalStructure Description
5-Aminolevulinic acid HCl Chemical Structure
Solubility (25C)
DMSO 34 mg/mL, Water 34 mg/mL, Ethanol 6 mg/mL
Storage
2 years -20CPowder, 2 weeks4Cin DMSO, 2 months-80Cin DMSO

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mg
Available: In stock
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