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PF-5274857

PF-5274857

Item no.	S2777-10mM
Manufacturer	Selleckchem
CASRN	1373615-35-0
Amount	10 mM/1 ml
Quantity options	10 mg 100 mg 1 g 10 g 10 mM/1 ml 5 mg 50 mg 5 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	CC1=CC(=C(N=C1)C2=CC(=NC=C2Cl)N3CCN(CC3)C(=O)CCS(=O)(=O)C)C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1373615-35-0'
Similar products	1373615-35-0
Available
Storage Conditions	2 years -80 in solvent
Information	PF-5274857 is a potent and selective Smoothened (Smo) antagonist, inhibits Hedgehog (Hh) signaling with IC50 and Ki of 5.8 nM and 4.6 nM, respectively, and can penetrate the blood–brain barrier.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

S2777-10mM-datasheet.pdf

S2777-10mM-safety-datasheet.pdf