Comparison

Tacrolimus (FK506) European Partner

Item no. S5003-50
Manufacturer Selleckchem
CASRN 104987-11-3
Amount 50 mg
Quantity options 100 mg 1 g 10 g 10 mM/1 mL 50 mg 500 mg 5 g
Category
Type Inhibitors
Specific against other
Smiles CC1CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC(=O)C(C=C(C1)C)CC=C)O)C)C(=CC4CCC(C(C4)OC)O)C)O)C)OC)OC
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias FR900506,Fujimycin
Similar products FK-506
Available
Storage Conditions
2 years -80 in solvent
Molecular Weight
804, 02
Solubility (25C)
DMSO 161 mg/mL, Water <1 mg/mL, Ethanol 161 mg/mL
Information
Tacrolimus (FK506) is a 23-membered macrolide lactone, it reduces peptidyl-prolyl isomerase activity in T cells by binding to the immunophilin FKBP12 (FK506 binding protein) creating a new complex. Tacrolimus also inhibits the phosphatase activity of calcineurin. Tacrolimus induces vascular endothelial autophagy.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
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