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Thapsigargin

Thapsigargin

Item no.	S7895-1
Manufacturer	Selleckchem
CASRN	67526-95-8
Amount	1 mg
Quantity options	1 mg 10 mM/1 mL 5 mg
Category	Cardiovascular Research Ischemia & Reperfusion Injury Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	CCCCCCCC(=O)OC1C2C(=C(C1OC(=O)C(=CC)C)C)C3C(C(CC2(C)OC(=O)C)OC(=O)CCC)(C(C(=O)O3)(C)O)O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	67526-95-8'
Available
Manufacturer - Targets	ATPase
Storage Conditions	3 years -20°C powder
Information	Thapsigargin is a potent, non-competitive inhibitor of the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) with IC50 of 0.353 nM or 0.448 nM for the carbachol-evoked [Ca2+]i-transients with or without a KCl-prestimulation. Thapsigargin induces cell apoptosis. Thapsigargin is extracted from a plant, Thapsia garganica.
Pathway	Transmembrane Transporters

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

S7895-1-datasheet.pdf

S7895-1-safety-datasheet.pdf