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Acolbifene

Acolbifene

Item no.	TMO-T10239-25mg
Manufacturer	TargetMol
CASRN	182167-02-8
Amount	25 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 1 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	0,98
Formula	C29H31NO4
Smiles	CC1=C([C@@H](Oc2cc(O)ccc12)c1ccc(OCCN2CCCCC2)cc1)c1ccc(O)cc1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	EM-652,SCH 57068
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Estrogen Receptor/ERR
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	457.56
Description	Acolbifene (SCH 57068) is a selective antagonist of estrogen receptors with IC50s of 2 nM and 0.4 nM for estradiol-induced transcriptional activity of ERα and ERβ. Acolbifene shows an anticarcinogenic property.
Pathways	Endocrinology/Hormones
Bioactivity	Acolbifene is a selective antagonist of estrogen receptors with IC50s of 2 nM and 0.4 nM for estradiol-induced transcriptional activity of ERÎ± and ERÎ². Acolbifene shows an anticarcinogenic property.

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