Comparison

AKT-IN-3 European Partner

Item no. TMO-T10275-5mg
Manufacturer TargetMol
CASRN 2374740-21-1
Amount 5 mg
Quantity options 100 mg 25 mg 500 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 0,98
Smiles CNC(=O)C[C@@H]1C[C@H]([C@@H](CN1)NC(=O)c1cc(c(Cl)o1)-c1c(Cl)cnn1C)c1ccc(F)c(F)c1
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias Akt
Shipping Condition Cool pack
Available
Manufacturer - Targets
Akt
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
526.36
Description
AKT-IN-3 is a potent, orally active low hERG blocking Akt inhibitor (IC50: 1.4 nM, 1.2 nM, and 1.7 nM for Akt1, Akt2, and Akt3). AKT-IN-3 (compound E22) also exhibits good inhibitory activity against other AGC family kinases, such as PKA, PKC, ROCK1, RSK1, P70S6K, and SGK.
Pathways
PI3K/Akt/mTOR signaling|||Cytoskeletal Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 mg
Available: In stock
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