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CGP52411

CGP52411

Item no.	TMO-T10782-25mg
Manufacturer	TargetMol
CASRN	145915-58-8
Amount	25 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	O=C1NC(=O)c2cc(Nc3ccccc3)c(Nc3ccccc3)cc12
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	DAPH
Shipping Condition	Cool pack
Available
Manufacturer - Targets	EGFR\|\|\|Beta Amyloid
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	329.35
Description	CGP52411 is an orally active, and ATP-competitive inhibitor of EGFR (IC50: 0.3 μM). CGP52411 blocks the toxic influx of Ca2+ ions into neuronal cells and dramatically inhibits and reverses the formation of β-amyloid Aβ42 fibril aggregates. CGP52411 can be used in studies about Alzheimer's diseases.
Pathways	Angiogenesis\|\|\|Neuroscience\|\|\|JAK/STAT signaling\|\|\|Tyrosine Kinase/Adaptors

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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